Including accommodations, transportation, and activities/tours.
Any specific destinations or interests (e.g. culture, food, wine, romance, adventure, wildlife, etc.)? Special occasion? Relaxing vs. fast-paced trip? What would make this your dream trip?
When renting a car, inspect the vehicle with the sales rep and document with photos any dents, dings, or damages prior to leaving the rental company to avoid any back and forth on its return.